HEPARAN SULFATE PROTEOGLYCANS: KEY MEDIATORS OF STEM CELL FUNCTION

Heparan Sulfate Proteoglycans: Key Mediators of Stem Cell Function

Heparan sulfate proteoglycans (HSPGs) are an evolutionarily ancient subclass of glycoproteins with Family exquisite structural complexity.They are ubiquitously expressed across tissues and have been found to exert a multitude of effects on cell behavior and the surrounding microenvironment.Evidence has shown that heterogeneity in HSPG composition i

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Selection-Mutation Dynamics of Signaling Games

We study the structure of the rest points of signaling games and their dynamic behavior under selection-mutation dynamics by taking the case of three signals as our canonical example.Many rest points of the replicator dynamics of signaling games are not isolated and, therefore, not robust under perturbations.However, some of them attract open Skill

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